FABRE, VIRGINIE,ROCCA, CÉLINE,RIFFARD, PIERRE,CALVOSA, ERIC
申请号:
EP10723229.0
公开号:
EP2417251B1
申请日:
2010.04.08
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.