A number of gallbladder treatment devices and methods treating gallstone disease are included. A gallbladder treatment device has a structure secured within the gallbladder to maintain gallstones and gallstone fragments within the gallbladder interior and distal to the gallbladder neck. A gallbladder treatment device may be put into therapeutic use by first accessing the gallbladder interior and then advancing the gallbladder treatment device into the gallbladder interior. The gallbladder treatment device is then positioned within the gallbladder interior in an orientation to maintain gallstones and gallstone fragments on one side of the device and away from or distal to the gallbladder neck.
