Jeffrey L. Goldberg,Vance P. Lemmon,John Bixby,Darcie Moore,Murray Blackmore
申请号：
US13394068
公开号：
US08609617B2
申请日:
2010.09.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention relates, to a method for promoting CNS axon regeneration, comprising (1) inhibiting the expression or activity in a neuron of one or more of the members of the Krüppel-like transcription factor (KLF) family that suppress axon growth (e.g., KLF 1, 2, 3, 4, 5, 9,12, 13, 14, 15 and/or 16), and/or (2) stimulating the expression or activity in a neuron of one or more of the members of the KLF family that promote axon growth (e.g., KLF 6 and/or 7).
