Macdonald Lynn,Gao Min,Morra Marc. R.,Alessandri-Haber Nicole M.,Lacroix-Fralish Michael L.
申请号：
NZ62624213
公开号：
NZ626242A
申请日:
2013.01.30
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
The present invention provides isolated human monoclonal antibodies, or antigen-binding fragments thereof, that specifically bind cell surface-expressed ASIC1 and inhibit acid-induced ASIC1-mediated ion currents. The antibodies of the invention are useful for the treatment of pain, including pain associated with surgical intervention and various diseases and disorders.
