COMPOSITION COMPRISING A COMBINED HERB EXTRACT OF SALVIA PLEBIA AND RED GINSENG AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING A RESPIRATORY INFLAMMATION AND THE USE THEREOF
Han-Jae SHIN,Hyo Keun KIM,Moon-Yong LEE,Hyo-Min GWAK,Hye-Jeong MIN,Young-Sin KIM,Chang Kyun HAN,Jongsu KYUNG,Gyo IN,Jong Han KIM,Sung Won KIM,Kyoung Hwa JANG,Seung-Hyung KIM
申请号：
US16611836
公开号：
US20200164016A1
申请日:
2018.05.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1)； Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2)； Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3)； Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4)； Lung histology (Experimental Example 5)； Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract. Therefore, the herbal extract of the present invention can be usefully used in a pharmaceutical composition, health functional food, and health supplement food for preventing and treating respiratory inflammation disease.
