An orthopedic or therapeutic support pillow is provided for use by a patient to support an arm and shoulder while the patient is resting in a generally prone position on a resting surface. The pillow includes a back section for positioning and supporting the pillow on resting surface, the back section having a central memory foam section to adapt to the contour of the body of the patient. The pillow further includes a pair of side arms extending from the back section, each side arm including contoured areas and a plush thickness to support the body, arms, and shoulders. The back section includes shoulder support zones to engage and support the shoulders of the patient when reclining on the pillow.