A prosthetic device (10) for repairing or augmenting a tissue, muscle or organ defect is disclosed. It comprises a first portion (12) of biological tissue that is remodelable and configured for tissue ingrowth. The first portion being constructed and arranged to cover or plug a defect and a second portion (14) of biological tissue that is more slowly enzymatically degradable after implantation than the first layer and that is not configured for tissue ingrowth. The second portion has sufficient pullout strength so that said prosthetic device is fixatable through said second portion.
