LISA MARIE FROST,STEPHEN MARTIN COURTNEY,FREDERICK ARTHUR BROOKFIELD,VINCENT J. KALISH
申请号：
PT09743703
公开号：
PT2278975T
申请日:
2009.05.07
申请国别(地区):
PT
年份:
2016
代理人:
摘要：
The invention relates to nitroso derivatives including carboxylic acid and phosphoric acid esters of hydroxy nitroso compounds that donate nitroxyl (HNO) under physiological conditions. The compounds and compositions of the invention are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure, ischemia/reperfusion injury and cancer.
