Systems and methods include a cutting instrument that creates incisions in selected areas of the cornea an eye therapy system that applies reshaping forces to the cornea and a controller that determines the selected areas of the cornea for the incisions and the reshaping forces from the eye therapy system, such that the reshaping forces and the incisions combine to achieve corrective reshaping of the cornea. Other systems and methods include measuring an eye to determine a required amount of reshaping of a cornea determining one or more doses of cross-linking agent and one or more corresponding doses of photoactivating light according to the required amount of reshaping applying the cross-linking agent to the cornea and delivering, from a light source, the photoactivating light to the area of the eye, the photoactivating light combining with the cross-linking agent to induce the corrective reshaping of the cornea.