The invention provides compounds of the Formula (I) or a pharmaceutically acceptable salts thereof, wherein X, Y, Z, R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>；, R<；sup>；4<；/sup>；, Ra, and the subscripts m, p, and q are as described herein. The compounds or their pharmaceuticallacceptable salts can modulate the body's production of cyclic guanosine monophosphate ("cGMP"), and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention also relates to methods for use of the compounds or theipharmaceutically acceptable salts in the therapy and prophylaxis of the abovementioned diseasesand for preparing pharmaceuticals for this purpose.
