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Human antibody specific to c-Met and preparation method thereof
专利权人:
发明人:
Jinsang Yoo,Ju Ryoung Nam,Jin San Yoo,Sung-Woo Kim,Weon Sup Lee,Sang Ryeol Shim,Sang Soon Byun,Miju Park,Hyuk Joon Lee,Do Yun Kim,Yeon Ju Kim,Mi Ae Jeon,Jinhee Choi,Youngae Lee,Kyoung Hee Nahm,Boyoung
申请号:
US15501843
公开号:
US10106622B2
申请日:
2015.07.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are an antibody specifically bound to c-Met (c-Met-specific antibody) or fragments thereof, and more specifically, a fully human antibody having high affinity and specificity to c-Met isolated from human Fv(ScFv) phage library, a polynucleotide encoding the antibody, a recombinant vector containing the polynucleotide, a cell transformed with the recombinant vector, and a method of producing the c-Met-specific antibody by culturing the cell, wherein the c-Met-specific antibody may effectively control activity of c-Met in vivo.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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