HANSEN, HANS J.,CHANG, CHIEN-HSING,GOLDENBERG, DAVID M.
申请号:
EP10817617
公开号:
EP2478110A4
申请日:
2010.07.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention concerns a composition and a method for use of such composition wherein the composition comprising a chimeric, humanized or human Class I anti-CEA antibody or antigen-binding fragment thereof, comprising the light chain variable region CDR (complementarity determining region) sequences SASSRVSYIH (SEQ ID NO:1) GTSTLAS (SEQ ID NO:2) and QQWSYNPPT (SEQ ID NO:3) and heavy chain variable region CDR sequences DYYMS (SEQ ID NO:4) FIANKANGHTTDYSPSVKG (SEQ ID NO:5) and DMGIRWNFDV (SEQ ID NO:6).