Carbamate [4,5-c] quinine-2-ona as PI3K / mTOR inhibitor

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专利权人:

ELI LILLY AND COMPANY

发明人:

BARDA, DAVID ANTHONY,MADER, MARY MARGARET

申请号：

PE2013001553

公开号：

PE20140864A1

申请日:

2012.01.11

申请国别(地区):

PE

年份:

2014

代理人:

摘要：

It refers to compound 8 - [5 - (1-hydroxi-1-methyl) piridin-3-il] - 1 - [(2S) - 2-methylpropil] - 3-methyl-1, 3-dihydro-2h-imidazo [4, 5-c] quinolin-2-ona, or a salt thereof. It also refers to a crystalline form and a drug synthesis. This compound is an effective drug for the treatment of bladder cancer, pancreatic cancer, renal cancer, melanoma and scabies.SE REFIERE AL COMPUESTO 8-[5-(1-HIDROXI-1-METILETIL)PIRIDIN-3-IL]-1-[(2S)-2-METOXIPROPIL]-3-METIL-1, 3-DIHIDRO-2H-IMIDAZO [4, 5-C]QUINOLIN-2-ONA, O UNA SAL DEL MISMO. REFERIDO TAMBIEN A UNA FORMA CRISTALINA Y A UNA COMPOSICION FARMACEUTICA. DICHO COMPUESTO ES UTIL PARA EL TRATAMIENTO DE CANCER DE VEJIGA, CANCER PANCREATICO, CANCER RENAL, MELANOMA, SARCOMA

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