The present invention relates to a pharmaceutical composition useful for the treatment or prevention of stress-related disorders, depression, and anxiety disorders, containing 5-benzylaminosalicylic acid derivatives and/or pharmaceutically acceptable salts thereof as active ingredients. In addition, the present invention relates to a method for treating or preventing stress-related disorders, depression, and anxiety disorders, wherein the method comprises a step for administrating 5-benzylaminosalicylic acid derivatives and/or pharmaceutically acceptable salts thereof to a subject required for treatment.