JENKINS, Russell,BARBIE, David,PAWELETZ, Cloud,IVANOVA, Elena,AREF, Amir
申请号：
SG11201908240Y
公开号：
SG11201908240YA
申请日:
2018.03.30
申请国别(地区):
SG
年份:
2019
代理人:
摘要：
MicrofluidicD Culture Serial Microscopy (Live/Dead Analysis) Tumor Specknen Sequential filtration Physical+ enzymatic dissociation. Flow cytometry 105 CD6 T cells 104 1 10 01 -10- -10 3 0 10 3 10 4 10 3 -1 " 1CD4 T cells 56.9 10 4 10 5 Lyrrionacytes 19.3 lexCytokine P iling of Conditioned Media FIG. 1A Murine- derived Patient- derived GO Go Go 00 O C (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) CORRECTED VERSION (19) World Intellectual Property Organization International Bureau (43) International Publication Date 111111111111011010101111101111010 I011111101111111100HORIOVE# (10) International Publication Number WO 2018/183839 A8 04 October 2018 (04.10.2018) Wi PO I PCT (51) International Patent Classification: Lane, Andover, MA 01810 (US). PAWELETZ, Cloud, P.； 9618 3 9 / 3 95 (2006.01) A61K 49/06 (2006.01) 725 Harrison Ave #404, Boston, MA 02118 (US). IVANO- 9618 49/00 (2006.01) 9618 4 9 / 1 6 (2006.01) VA, Elena； 100 Marion Street, #27, Brookline, MA 02446 9618 49/04 (2006.01) 9618 4 9 / 1 8 (2006.01) (US). AREF, Amir； 179 Gerry Road, Chestnut Hill, MA (21) International Application Number: PCT/US2018/025390 (22) International Filing Date: 30 March 2018 (30.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/480,192 31 March 2017 (31.03.2017) US (71) Applicant: DANA-FARBER CANCER INSTITUTE, INC. [US/US]； 450 Brookline Avenue, Boston, MA 02215 (US). (72) Inventors: JENKINS, Russell, W.； 1 Canal Street, Unit 626, Boston, MA 02114 (US). BARBIE, David； 2 Harwich 02467 (US). (74) Agent: BERKEY, Cristin； Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210-2206 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP,
