Eric A. Schmitt;Ping Tong;Geoff G. Z. Zhang;Deliang Zhou;Cristina M. Fischer;Katherine Heemstra;Nathaniel Catron;Yeshwant D. Sanzgiri;Anthony R. Haight;Michael G. Fickes
发明人:
Nathaniel Catron,Michael G. Fickes,Cristina M. Fischer,Anthony R. Haight,Katherine Heemstra,Yeshwant D. Sanzgiri,Eric A. Schmitt,Ping Tong,Geoff G. Z. Zhang,Deliang Zhou
申请号：
US12770174
公开号：
US08728516B2
申请日:
2010.04.29
申请国别(地区):
US
年份:
2014
代理人:
摘要：
An orally deliverable pharmaceutical composition comprises a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
