Université Paris-Est Créteil Val de Marne;Centre National de la Recherche Scientifique (C.N.R.S.);Institut National de la Santé et de la Recherche Médicale (INSERM)
发明人:
MOTTERLINI, Roberto,FORESTI, Roberta,MARTENS, Thierry,RIVARD, Michael
申请号：
ES15710821
公开号：
ES2718548T3
申请日:
2015.03.20
申请国别(地区):
ES
年份:
2019
代理人:
摘要：
The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases.
