表面改質剤、細胞親和性材料、細胞親和性材料の製造方法並びに、骨様移植物及び骨様移植物の製造方法。
- 专利权人:
- 学校法人東京理科大学
- 发明人:
- 好野 則夫,齋藤 正寛,寺中 敏夫,二瓶 智太郎,尾本 直大,大橋 桂
- 申请号：
- JP2005059750
- 公开号：
- JP4871519B2
- 申请日:
- 2005.03.03
- 申请国别(地区):
- JP
- 年份:
- 2012
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a cytophilic material which ensures both biological functions and mechanical properties near to those of bone tissues in living bodies, and to simply provide a bone-like transplant using the cytophilic material.
SOLUTION: An amide derivative represented by the general formula: A-(Sp)-B or B-(Sp)-A-(Sp)-B (A is an amide bond-containing portion having a specific NR
1 CO structure which may form a ring capable of binding to Sp or B Sp is a spacer portion which may be present or absent B is at least one substrate-binding portion selected from the group consisting of specific structure silyl groups capable of binding to Sp or A and also capable of binding to polar group-containing substrates, and phosphate esters and phosphate ester salts having specific structures). The surface-modifying agent comprising the amide derivative. The cytophilic material obtained by treating the surface of the polar group-having substrate with the surface-modifying agent.COPYRIGHT: (C)2006,JPO&NCIPI
- 来源网站：
- 中国工程科技知识中心
