Vinod Labhasetwar,Jaspreet K. Vasir,Maram K. Reddy
申请号:
US15097757
公开号:
US10016488B2
申请日:
2016.04.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A sustained-release composition for stimulating endothelial cell growth including a nitric oxide synthase within a nanoparticle comprising a biocompatible polymer is described. The sustained-release composition can be administered as part of a pharmaceutical composition, or can be coated on a medical device. The nitric oxide synthase-containing nanoparticles can be used in a method of inducing endothelium formation in a blood vessel.