WOUTER DE GRAAFF,RUDOLF JOHANNES JOSEPH GROENEWEGEN,HENK JAN OUT
申请号：
PT04741599
公开号：
PT1631255E
申请日:
2004.05.19
申请国别(地区):
PT
年份:
2013
代理人:
摘要：
The subject invention provides a drug delivery system comprising at least one compartment consisting of (i) a drug-loaded thermoplastic polymer core, (ii) a drug-loaded thermoplastic polymer intermediate layer and (iii) a non-medicated thermoplastic polymer skin covering the intermediate layer, wherein said intermediate layer is loaded with (a) crystals of a first pharmaceutically active compound and with (b) a second pharmaceutically active compound in dissolved form and wherein said core is loaded with said second compound in dissolved form.
