Joseph L. Duffy,Jianming Bao,Debra L. Ondeyka,Sriram Tyagarajan,Patrick Shao,Feng Ye,Revathi Katipally,Paul E. Finke,Yi Zang,Michael A. Plotkin,F. Anthony Romero,Remond Moningka,Zahid Hussain
申请号:
US13641767
公开号:
US20130040978A1
申请日:
2011.05.13
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.