A balloon catheter including a catheter shaft and an inflatable balloon secured to a distal end region of the catheter shaft. The inflatable balloon has a generally conical shape in a fully inflated configuration having a proximal conical portion that tapers away from the central longitudinal axis in a distal direction from a proximal waist of the balloon and a distal conical portion that tapers toward the central longitudinal axis in a distal direction toward a distal waist of the balloon, with a radially outermost extent of the balloon located between the proximal conical portion and the distal conical portion. The proximal conical portion, the distal conical portion and/or the radially outermost extent of the balloon has an elliptical cross-section taken in a plane perpendicular to the central longitudinal axis of the catheter shaft.