A system and method for generating a rib suppressed radiographic image using deep learning computation. The method includes using a convolutional neural network module trained with pairs of a chest x-ray image and its counterpart bone suppressed image. The bone suppressed image is obtained using a bone suppression algorithm applied to the chest x-ray image. The convolutional neural network module is then applied to a chest x-ray image or the bone suppressed image to generate an enhanced bone suppressed image.
