Systems and methods for securing a drug delivery system to the body of a person are provided. The drug delivery system can include a pad coupled to a bottom of the drug delivery system. A bottom surface of the pad can include an adhesive for attaching to a user of the drug delivery system. An adhesive overlay can be positioned over the drug delivery system to improve attachment of the drug delivery system to the patient. The adhesive overlay can include an interior cutout that fits over the drug delivery system. A first portion of the adhesive overlay can adhere to the pad of the drug delivery system and a second portion of the adhesive overlay can adhere to the skin of the user. The adhesive overlay can have a larger surface area than the pad to improve the attachment of the drug delivery system to the user.