Wolfgang Teschner,Yendra Linnau,Sonja Svatos,Herwig Igel
申请号:
US14264369
公开号:
US20140234292A1
申请日:
2014.04.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
There is disclosed a method of preparing a plasma protein-containing medicament from citrated plasma or from a citrate-containing plasma fraction, the medicament being substantially free from undesired metals, which method comprises the following stepsexchanging the citrate and optionally citrate-bound metals in a plasma-protein-containing solution for a water-soluble mono- or dicarboxylate or for an organic mono- or dicarboxylic acid under non-precipitating conditions,recovering the plasma protein or the plasma proteins, andfinishing the medicament.