Peritoneal dialysis systems and methods are provided by the present disclosure. In a general embodiment, a peritoneal dialysis system includes a peritoneal dialysis fluid supply, a supply line in fluid communication with the peritoneal dialysis fluid supply and terminating at a supply connector, a patient connector in fluid communication with a patient's indwelling catheter, a device configured to connect the supply connector to the patient connector without a user having to physically contact the supply connector or the patient connector, and a housing placeable around the connecting device and including a plurality of ultraviolet (“UV”) light-emitting diodes (“LED's”) positioned to direct energy towards at least one of the supply connector and the patient connector.