An apparatus is disclosed for a biofunctional molecular imprint apparatus comprising a supportive structure that cuts, punctures, retains, repairs, protects, interrogates, and/or supports the function of a body tissue or other substance； a surface material that receives and retains a molecular imprint and that is positioned to contact the body tissue or other substance during use； and a molecular imprint of a bioactive molecule that influences blood coagulation, tissue damage, pain, immune response, inflammation, infection, healing, tissue regeneration, cell adhesion, the formation of extracellular matrix, tumorigenesis, angiogenesis, bacterial growth, and/or side effects.
