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BIOCOMPATIBLE IMPLANTS FOR NERVE RE-GENERATION AND METHODS OF USE THEREOF
专利权人:
Rutgers; The State University of New Jersey
发明人:
Joachim B. Kohn,Basak Clements,Mindy Ezra
申请号:
US15566552
公开号:
US20180280567A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A biocompatible nerve conduit for nerve re-generation, wherein a porous fiber tube is coated with a bioresorbable hydrogel, with the fibers being formed from a polymer that supports nerve regeneration by preferential adsorption of endogenous proteins and braided with pores in the range from 5 to 200 micrometers using a kink-resistant braiding pattern and the hydro gel coating material and thickness being selected to control the overall porosity, so that nutrients and oxygen can diffuse through said hydrogel coating but the infiltration of fibrous tissue through the coating is prevented.
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