#$%^&*AU2006203713B220120927.pdf#####ABSTRACT Systems and methods are provided for registering maps with images, involving segmentation of three-dimensional images and registration of images with 5 an electro-anatomical map using physiological or functional information in the maps and the images, rather than using only location information. A typical application of the invention involves registration of an electro-anatomical map of the heart with a preacquired or real-time three-dimensional image. Features such as scar tissue in the heart, which typically exhibits lower voltage than healthy tissue in the electro10 anatomical map, can be localized and accurately delineated on the three-dimensional image and map. 24/08/06,15888 speci,21/5 -44 cc cm M CQ CQ C12 co CV CQ r