Provided are a fusion protein that suppresses the formation or growth of blood vessels, a coding sequence thereof, a vector containing the coding sequence, a host cell, a pharmaceutical composition, and uses of the fusion protein. The fusion protein provided by the present invention has high thermal stability, significantly lowers the rate of protein polymer formation in the fermentation process, significantly improves protein purity and yield, and has excellent biological activity. [Selection] Figure 2血管の新生又は成長を抑制する融合タンパク質、そのコード配列、該コード配列を含むベクター、宿主細胞、医薬組成物及び前記融合タンパク質の用途を提供する。本発明で提供する融合タンパク質は熱的安定性が高く、発酵過程におけるタンパク質重合体の形成率を顕著に低下させ、タンパク質の純度と収率を顕著に向上させ、優れた生物活性を有する。【選択図】図２
