THE REGENTS OF THE UNIVERSITY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
申请号:
IL23664415
公开号:
IL236644D0
申请日:
2015.01.11
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
The present invention provides methods for determining the selectivity of an anesthetic for an anesthetic-sensitive receptor by determining the molar water solubility of the anesthetic. The invention further provides methods for modulating the selectivity of an anesthetic for an anesthetic-sensitive receptor by altering or modifying the anesthetic to have higher or lower water solubility. The invention further provides methods of inducing anesthesia in a subject by administering an effective amount of an anesthetic compound identified according to the present methods.