具有EP4受體活性的經取代之苯甲醯胺农业专利-农业学术服务平台

专利权人:: DRACONIS PHARMA, S.L.;ALMIRALL;LABORATORIOS DEL DR. ESTEVE, S. A.;ALMIRALL, S. A.; S. A.

发明人:: VIRGILI BERNADO, MARINA,费吉利　本纳多　玛琍娜,費吉利　本納多　瑪琍娜,CARCELLER GONZALEZ, ELENA,卡拉西列　康那列兹　爱莲那,卡拉西列　康那列茲　愛蓮那,SALAS SOLANA, JORDI,萨拉斯　索那拉　尤维,薩拉斯　索那拉　尤維,费吉利本纳多玛琍娜,費吉利本納多瑪琍娜,卡拉西列康那列兹爱莲那,卡拉西列康那列茲愛蓮那,萨拉斯索那拉尤维,薩拉斯索那拉尤維

摘要：: The present invention belongs to the field of EP4 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP4 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP4 receptor as well as to pharmaceutical compositions comprising them.本發明屬於EP4受體配體的技術領域。更明確言之，本發明是關於對EP4受體具有高親和力和選擇性的通式(I)化合物。本發明亦有關用於製備該等化合物的製程、該等化合物作為藥物以供治療及/或預防EP4受體所介導之疾病或不適的用途及含有該等化合物的藥學組成物。