NON-HUMAN MAMMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES

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专利权人:

LLC;ABLEXIS

发明人:

GREEN, LARRY,SHIZUYA, HIROAKI

申请号：

NZ59230809

公开号：

NZ592308A

申请日:

2009.09.30

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a non-human mammalian cell having a genome comprising (1) a human VH gene segment operably linked to (2) a portion of an Ig heavy chain locus, said portion comprising one or more non-human heavy chain constant region gene segments and a human CH1 domain, wherein said cell comprises a genome encoding a chimeric Ig heavy chain.

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中国工程科技知识中心

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http://www.ckcest.cn/home/