Disclosed are methods, devices, and techniques useful for enhancing function of an organ or cellular graft through administration of light frequencies sufficient to enhance desired therapeutic activity. In one embodiment a bone marrow cellular population is treated with one or more wavelengths of low level laser irradiation at a sufficient energy to enhance engraftment, trophic, and regenerative activity in the corpus cavernosum. In another embodiment the recipient penile body is treated with one or more wavelengths of low level laser irradiation at a sufficient energy to enhance chemoattraction and growth factor secretion.