The invention discloses an anti-dumping transport box for medical drugs, which includes a box body. The box body is provided with a cavity. The cavity is provided with a clamping mechanism. The clamping mechanism passes through a sealing plate and a packaging box. Five test tubes can be clamped, the medicine is stored in the storage chamber in the test tube, and the sealing piston in the clamping mechanism can seal the storage chamber. The present invention can hold the test tube vertically and pass The sealed piston is sealed to prevent leakage of the drug, and to keep the drug in an environment filled with inert gas, to prevent gas with more impurities such as air from entering the test tube and contaminating the drug, and to reduce the upper and lower test tubes during transportation. The amplitude of the vibration and the angle of inclination can prevent the tube from leaking the drug due to the large inclination.