The present invention relates to an insect disinfection device with automatic medicine supply, comprising: an insect disinfection base, a liquid storage container and a carrier. The insect disinfection comprises a containing portion and a connection portion, the inside of the liquid storage container stores insecticide and connects with the connection portion, so the insecticide flows into the inside of the containing portion and forms. The horizontal plane aligns an open of the connection portion. The carrier is provided with a soak portion and a volatile portion. Wherein, the soak portion is soaked in the insecticide which is inside the insect disinfection base; the soak portion will absorb the insecticide so the volatile portion will contain the insecticide as well.Therefore, when there is insecticide inside the liquid storage container, the horizontal plane of insecticide would still align the open. The soak portion of carrier soaked in the insecticide continuously, the insecticide of the volatile portion will be kept in certain concentration, so the insect disinfection function would be stable and kept for a long time.本發明自動供藥滅蟲裝置,包含:滅蟲座體、儲液容器與載體,該滅蟲座體具有容置部與連接部,而儲液容器的內部存放滅蟲藥劑,並連接於連接部,使滅蟲藥劑能流入容置部內以形成水平面,而水平面切齊於一位在連接部內的液面開孔,而載體區分為浸泡部與揮發部,其中,浸泡部浸泡於位在滅蟲座體內的滅蟲藥劑,使浸泡部吸取滅蟲藥劑而讓揮發部含有滅蟲藥劑,藉此,在儲液容器內部還有滅蟲藥劑的狀態下,滅蟲藥劑的水平面會持續切齊於液面開孔,使載體的浸泡部能持續浸泡於滅蟲藥劑,進而位在揮發部的滅蟲藥劑能長時間保持在特定濃度,致使滅蟲效果就能保持非常穩定與持久。