The disclosure provides a pharmaceutical composition for retarding liver cancer growth, improving liver function, liver fibrosis, liver cirrhosis and liver inflammation, and promoting damaged liver regeneration, including: a proanthocyanidin with an effective amount； and a pharmaceutically acceptable carrier or salt, wherein the monomer units of the proanthocyanidin have the following formula.In the formula, when R1 is OCH3, R2 is OH and R3 is H, when R1 is OH, R2 is H and R3 is H, when R1 is OH, R2 is OH and R3 is H, or when R1 is OH, R2 is OH and R3 is OH, and R4 is 3-(α)-OH, 3-(β)-OH, 3-(α)-O-sugar or 3-(β)-O-sugar.
