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IL-2 peptide derivatives, and uses thereof for the diagnosis and treatment of an autoimmune disease
专利权人:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);INSTITUT CURIE;UNIVERSITE PARIS DESCARTES
发明人:
Eliane Piaggio,Louis Perol
申请号:
US15305548
公开号:
US10114018B2
申请日:
2015.04.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An in vitro method for determining whether a patient has, or is at risk of having or developing an autoimmune disease or for assessing the severity or predicting the outcome of an autoimmune disease, comprising a step of detecting or quantifying in a biological sample obtained from said patient an immune anti-IL2 response, peptides specifically recognized by anti-IL2 antibodies or IL-2-specific T cells of T1D, systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome and autoimmune polymyositis patients, and pharmaceutical compositions.
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