The U.S.A. as represented by the Secretary; Department of Health and Human Services;THE U S A AS REPRESENTED BY THE SEC DEP OF HEALTH AND HUMAN SERVICES
发明人:
申请号：
EP14750663.8
公开号：
EP3027612B1
申请日:
2014.07.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The disclosure includes compounds and pharmaceutically acceptable salts of Formula (I). Certain compounds and salts of Formula (I) are selective inhibitors of the Dopamine D2 receptor. The variables R1-R4, n, and L are defined herein. The disclosure also provides methods of synthesizing compounds of Formula (I) and pharmaceutical compositions containing compounds of Formula (I). Additionally the disclosure provides methods or treating patients suffering from central nervous system disorders, including Tourette's syndrome, bipolar disorder, hyperprolactinemia, tardive dyskinesia, Huntington's chorea, psychosis, depression, or schizophrenia.
