An in vitro human neural multipotent, unipotent, or somatic cell possessing all of the following characteristics: is derived from the reprogramming of a somatic cell, a progenitor cell or a stem cell that exhibits at least a transient increase in intracellular levels of at least one reprogramming agent； is not differentiated from a pluripotent cell； expresses one or more markers of a multipotent, unipotent or somatic cell not characteristic of a neural stem cell, neural precursor cell, neural progenitor cell, neuroblast, or neuron； is not a cancerous cell； is stable and not artificially maintained by forced gene expression and may be maintained in standard neural stem cell media or neural media； and does not exhibit uncontrolled growth, teratoma formation, and tumor formation in vivo； wherein the cell comprises at least one polypeptide or an expression vector encoding at least one polypeptide selected from the group consisting of: Musashi1 (Msi1)； Ngn2； Msi1 and Ngn2； Msi1 and methyl-CpG binding domain protein 2 (MBD2)； Ngn2 and MBD2； Msi1, Ngn2 and MBD2； Achaete-Scute Homolog 1 (Ascl1)； Msi1, Ngn2 and Ascl1； Msi1, Ngn2, MBD2 and Ascl1； Sox2； Msi1, Ngn2 and Sox2； and Msi1, Ngn2, MBD2 and Sox2； wherein the expression vector is transiently expressed.
