製造(羥基烷基)吡咯衍生物之方法农业专利-农业学术服务平台

发明人:: NUSS, JOHN,努斯　约翰,努斯　約翰,WILLIAMS, MATTHEW,威廉　马修,威廉　馬修,MOHAN, RAJU,莫翰　拉如,MARTIN, RICHARD,马丁　理察,馬丁　理察,WANG, TIE-LIN,王泰霖,AOKI, KAZUMASA,青木一真,TSURUOKA, HIROYUKI,鹤冈弘幸,鶴岡弘幸,HAYASHI, NORIYUKI,林,努斯约翰,努斯約翰,威廉马修,威廉馬修,莫翰拉如,马丁理察,馬丁理察

摘要：: The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases. The compound is an atropisomer of a compound represented by the following general formula (I): wherein R1 represents a C1-C3 alkyl group； R2 represents a 2-hydroxy-C4-C6 alkyl group； R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like； R4 represents a hydrogen atom, a halogeno group and the like； R5 represents a C1-C3 alkyl group； and R6 represents a hydrogen atom, a halogeno group and the like] or atropisomers thereof.本發明包含用於預防及/或治療心血管疾病之化合物。該化合物係由下述通式(I)代表之化合物或其阻轉異構體：其中R1代表C1-C3烷基；R2代表2-羥基-C4-C6烷基；R3代表鹵素基團、鹵代C1-C3烷基及諸如此類；R4代表氫原子、鹵素基團及諸如此類；R5代表C1-C3烷基；且R6代表氫原子、鹵素基團及諸如此類。