#$%^&*AU2015203074B120161020.pdf#####Abstract Disclosed is a pharmaceutical composition for the treatment of Depression, wherein the pharmaceutical composition is consisted of the following herbs in weight parts: 2-10 parts 5 Ramulus Cinnamomi, 2-10 parts Rhizoma Zingiberis, 2-10 parts Fructus Schisandrae Chinensis, 2-8 parts Semen Ziziphi Spinosae, 2-8 parts Radix Codonopsis, 1-3 parts Rhizoma Dioscoreae, 0.5-2.5 parts Flos Inulae, 1-3 parts Caulis Bambusae in Taenia, 1-3 parts Fructus Trichosanthis, 1.5-4 parts Caulis Polygoni Multiflori, 1.5-4 parts Radix Ophiopogonis, 2-8 parts Radix Rehmanniae, 1.5-4 parts Cortex Moutan Radicis, 0.5-2.5 parts Fructus Gardeniae, 10 0.5-2.5 parts Herba Lophatheri, and 0.2-1.5 parts Folium Sennae. The pharmaceutical composition is applicable for liver and spleen deficiencies, depression caused by melancholy, prevalent mental depression, emotional discomfort, sluggish thinking, insomnia, chest tightness, irritability, bloating, belching, lassitude, sadness, lack of appetite, constipation, pink tongue, weak pulse. This invention also discloses a method for preparing the pharmaceutical 15 composition for treatment of Depression, which is easy to implement, simple, safe and reliable, and suitable for industrial scale production.