KIM, GWAN YOUNGKR,김관영,PARK, JUN HYUNGKR,박준형,RYU, KEUN HOKR,류근호,SHIN, HO CHULKR,신호철,HWANG, SANG WOOKKR,황상욱,KIM, HUN TAEKKR,김훈택,KWAK, YONG KYUKR,곽용규
申请号:
KR1020160027085
公开号:
KR1020160052472A
申请日:
2016.03.07
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
Provided is a slow-release oral preparation including a ginkgo leaf extract and a slow-release matrix system. The slow-release oral preparation containing the ginkgo leaf extract is capable of regulating the in-vivo absorption level for active components due to the controllable releasing speed. In addition, the preparation of the present invention exhibits continuous absorption owing to the delayed releasing speed, as the preparation passes through a gastrointestinal tract after being injected into the body, while continuously exhibiting antioxidant activity and a function of inhibiting platelet activating factor (PAF). Therefore, it is anticipated that the preparation brings highly therapeutic effects as well as an increase in adaptation to drugs in a patient by taking the preparation only once a day.COPYRIGHT KIPO 2016본 발명은 은행잎 추출물 및 서방성 매트릭스 시스템을 포함하는 서방성 경구용 제제를 제공한다. 본 발명에 따른 은행잎 추출물의 경구용 서방성 제제는 제어 가능한 방출 속도에 의해 활성성분의 생체내 흡수 정도를 조절할 수 있는데, 인체에 투여하였을 때 위장관을 통과하면서 지연된 방출 속도에 의해 지속적인 흡수를 나타내고 PAF(platelet activating factor) 억제작용 및 항산화작용을 지속적으로 나타내어 1일 1회 복용으로 환자의 복용순응도가 향상됨과 동시에 높은 치료효과를 기대할 수 있다.