NZ 603942 Disclosed is an isolated protein complex in the form of a synthetic chimeric protein, comprising an amino acid sequence of: keratinocyte growth factor (KGF), or at least a domain of KGF which is capable of binding a keratinocyte growth factor receptor; and one or more domains of vitronectin (VN) comprising at least an integrin-binding domain of VN. Also disclosed is the use of said protein complex in the manufacture of a medicament that induces, augments or otherwise promotes cell migration and/or proliferation.