#$%^&*AU2016208319A120160811.pdf#####ABSTRACT The present invention describes a method of quantifying microscopic diffusion anisotropy and/or mean diffusivity in a material by analysis of echo attenuation curves acquired with two different gradient modulations schemes, wherein one gradient modulation scheme is based on isotropic 5 diffusion weighting and the other gradient modulation scheme is based on non-isotropic diffusion weighting, and wherein the method comprises analyzing by comparing the signal decays of the two acquired echo attenuation curves.