TFPI-INHIBITORER OG FREMGANGSMÅDER TIL ANVENDELSE

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专利权人:

Baxalta GmbH

发明人:

REINEKE, Ulrich,OSTERKAMP, Frank,POLAKOWSKI, Thomas,DOCKAL, Michael,HARTMANN, Rudolf,FRIES, Markus,SCHEIFLINGER, Friedrich,EHRLICH, Hartmut

申请号：

DK11756689

公开号：

DK2547355T3

申请日:

2011.02.11

申请国别(地区):

DK

年份:

2017

代理人:

摘要：

The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, treat a blood coagulation disorder in a subject, purify TFPI, and identify a TFPI-binding compound.

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