Mary Callanan,Anouk Emadali,Myriam Ferro,Saadi Khochbin,Sophie Pison-Rousseaux
申请号：
US14371294
公开号：
US20150044201A1
申请日:
2013.01.10
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present disclosure concerns a method for the identification of the presence or absence of cancer cells in a biological sample, more particularly a method for the identification of the susceptibility or resistance to a treatment with CD20 agonists of cancer cells in a biological sample, the methods including determining the level of expression of the gene Cyclon in the cells and comparing the level of expression to the level of expression in a non-cancer cell, wherein a level of expression higher than the level of expression in a non-cancer cell is an indication of the presence of a cancer cell, more particularly an indication of cancer cells with a resistance to treatment with antagonists. Kits for the determination of a level of expression of the Cyclon gene in a biological sample, a method for the identification of Cyclon expression antagonists, and methods for treating patients are provided.
