The invention relates to a glasses provided with a light source for illuminating at least a portion of the eye of a subject wearing the glasses and relates to a system comprising such a glasses. The invention further relates to a system comprising the glasses of the invention and further comprising an external device provided with a processor as well as a computer program which, in use, causes the processor to control the at least one light source in the glasses in accordance with a predetermined program, wherein preferably the desired program is chosen by a wearer of the glasses. The invention also relates to a glasses case. The invention also relates to the glasses of the invention for use in a method of treatment of Parkinson's Disease by phototherapy.