Methods for treating conditions associated with masp-2 dependent complement activation

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专利权人:

UNIVERSITY OF LEICESTER;OMEROS CORPORATION

发明人:

DEMOPULOS GREGORY A.,DUDLER TOM,SCHWAEBLE HANS-WILHELM

申请号：

NZ70999712

公开号：

NZ709997A

申请日:

2012.04.06

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed is the use of a MASP-2 inhibitory agent which inhibits MASP-2-dependent complement activation in the manufacture of a medicament for treating a subject suffering from or at risk for developing non-Factor H-dependent atypical haemolytic uremic syndrome (aHUS), wherein the MASP-2 inhibitory agent is an anti-MASP-2 monoclonal antibody, or fragment thereof that specifically binds to a portion of mature human MASP-2 protein.

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中国工程科技知识中心

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