FIELD: medicine and veterinary medicine.SUBSTANCE: invention relates to the field of medicine, namely to veterinary medicine. Vein puncture is performed, an exfusion phase, on which a portion of blood is taken, a dose of an anticoagulant and a diluent from the reservoirs containing them is introduced therein, and the reinfusion phase on which the resulting exfusate is returned to the vein through a plasma filter with the simultaneous separation of plasma on it and cyclic repetition of the exfusion and reinfusion phases in which a portion of blood, the dose of anticoagulant and diluent is introduced into the straightening elastic chamber of the pump segment, which is previously compressed into the reinfusion phase. Volume of the exfusate is set by limiting the degree of straightening of the chamber of the pump segment, after which the reverse current of the anticoagulant and diluent in the decreasing containers and the exfusate in the vein and the plasma into the plasma filter is blocked in the beginning of the reinfusion phase. In this case, the initial clotting time of the animals blood is predetermined before the start of the procedure. Calculate the dose of anticoagulant and inject it intravenously before the procedure, and for the catheterization of the vein, the femoral or jugular vein, the central catheter is placed, or a peripheral catheter is placed on the subcutaneous vein of the thigh or shoulder of the animal. In this case, instead of the removed plasma, the saline solution is introduced, the volume of which is calculated depending on the degree of hydration of the animal, and during the procedure during the phase of exfusion, an anticoagulant is additionally administered. In addition, before catheter insertion in a vein, catheters are washed with an anticoagulant solution, and immediately after catheter insertion into the vein, the catheter is washed with saline and filled with an anticoagulant, forming an anticoagulant plug, the blood draw and recovery
